Computational Simulations to Guide Enzyme-Mediated Prodrug Activation

Prodrugs are designed to improve pharmaceutical/biopharmaceutical characteristics, pharmacokinetic/pharmacodynamic properties, site-specificity, and more. A crucial step in successful prodrug is its activation, which releases the active parent drug, exerting a therapeutic effect. Prodrug activation...

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Detalles Bibliográficos
Autores principales: Markovic, Milica, Ben-Shabat, Shimon, Dahan, Arik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279318/
https://www.ncbi.nlm.nih.gov/pubmed/32443905
http://dx.doi.org/10.3390/ijms21103621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279318/
https://www.ncbi.nlm.nih.gov/pubmed/32443905
http://dx.doi.org/10.3390/ijms21103621

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