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Synthetic Strategies and Computational Inhibition Activity Study for Triazinyl-Substituted Benzenesulfonamide Conjugates with Polar and Hydrophobic Amino Acids as Inhibitors of Carbonic Anhydrases

Various sulfonamide derivatives are intensively studied as anticancer agents owing to their inhibitory activity against human tumor-associated carbonic anhydrase isoforms. In this work, different synthetic procedures for the series of 1,3,5-triazinyl-aminobenzenesulfonamide conjugates with amino aci...

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Detalles Bibliográficos
Autores principales: Mikulová, Mária Bodnár, Kružlicová, Dáša, Pecher, Daniel, Supuran, Claudiu T., Mikuš, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279466/
https://www.ncbi.nlm.nih.gov/pubmed/32456080
http://dx.doi.org/10.3390/ijms21103661