APE1 Promotes Pancreatic Cancer Proliferation through GFRα1/Src/ERK Axis-Cascade Signaling in Response to GDNF

Pancreatic cancer is the worst exocrine gastrointestinal cancer leading to the highest mortality. Recent studies reported that aberrant expression of apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1) is involved in uncontrolled cell growth. However, the molecular mechanism of APE1 biological role...

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Detalles Bibliográficos
Autores principales: Choi, Yoo-Duk, Jung, Ji-Yeon, Baek, Minwoo, Khan, Sheema, Song, Peter I., Ryu, Sunhyo, Koo, Joo-Yeon, Chauhan, Subhash C., Tsin, Andrew, Choi, Chan, Kim, Won Jae, Kim, Mihwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279477/
https://www.ncbi.nlm.nih.gov/pubmed/32438692
http://dx.doi.org/10.3390/ijms21103586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279477/
https://www.ncbi.nlm.nih.gov/pubmed/32438692
http://dx.doi.org/10.3390/ijms21103586

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