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An Evaluation of the In Vitro Roles and Mechanisms of Silibinin in Reducing Pyrazinamide- and Isoniazid-Induced Hepatocellular Damage

Tuberculosis remains a significant infectious lung disease that affects millions of patients worldwide. Despite numerous existing drug regimens for tuberculosis, drug-induced liver injury is a major challenge that limits the effectiveness of these therapeutics. Two drugs that form the backbone of th...

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Detalles Bibliográficos
Autores principales: Goh, Zhang-He, Tee, Jie Kai, Ho, Han Kiat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279482/
https://www.ncbi.nlm.nih.gov/pubmed/32466226
http://dx.doi.org/10.3390/ijms21103714