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Structural Mechanisms of Store-Operated and Mitochondrial Calcium Regulation: Initiation Points for Drug Discovery

Calcium (Ca(2+)) is a universal signaling ion that is essential for the life and death processes of all eukaryotes. In humans, numerous cell stimulation pathways lead to the mobilization of sarco/endoplasmic reticulum (S/ER) stored Ca(2+), resulting in the propagation of Ca(2+) signals through the a...

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Detalles Bibliográficos
Autores principales: Noble, Megan, Lin, Qi-Tong, Sirko, Christian, Houpt, Jacob A., Novello, Matthew J., Stathopulos, Peter B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279490/
https://www.ncbi.nlm.nih.gov/pubmed/32455637
http://dx.doi.org/10.3390/ijms21103642