Cargando…
Structural Mechanisms of Store-Operated and Mitochondrial Calcium Regulation: Initiation Points for Drug Discovery
Calcium (Ca(2+)) is a universal signaling ion that is essential for the life and death processes of all eukaryotes. In humans, numerous cell stimulation pathways lead to the mobilization of sarco/endoplasmic reticulum (S/ER) stored Ca(2+), resulting in the propagation of Ca(2+) signals through the a...
Autores principales: | Noble, Megan, Lin, Qi-Tong, Sirko, Christian, Houpt, Jacob A., Novello, Matthew J., Stathopulos, Peter B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279490/ https://www.ncbi.nlm.nih.gov/pubmed/32455637 http://dx.doi.org/10.3390/ijms21103642 |
Ejemplares similares
-
Synergistic stabilization by nitrosoglutathione-induced thiol modifications in the stromal interaction molecule-2 luminal domain suppresses basal and store operated calcium entry
por: Novello, Matthew J., et al.
Publicado: (2020) -
Initial activation of STIM1, the regulator of store-operated calcium entry
por: Zhou, Yubin, et al.
Publicado: (2013) -
Mitochondrial Regulation of Store-operated Calcium Signaling in T Lymphocytes
por: Hoth, Markus, et al.
Publicado: (1997) -
STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry
por: Stathopulos, Peter B., et al.
Publicado: (2013) -
Store-Operated Calcium Channels as Drug Target in Gastroesophageal Cancers
por: Chang, Yan, et al.
Publicado: (2021)