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Mechanisms of Apoptosis Resistance to NK Cell-Mediated Cytotoxicity in Cancer

Natural killer (NK) cells are major contributors to immunosurveillance and control of tumor development by inducing apoptosis of malignant cells. Among the main mechanisms involved in NK cell-mediated cytotoxicity, the death receptor pathway and the release of granules containing perforin/granzymes...

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Detalles Bibliográficos
Autores principales: Sordo-Bahamonde, Christian, Lorenzo-Herrero, Seila, Payer, Ángel R., Gonzalez, Segundo, López-Soto, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279491/
https://www.ncbi.nlm.nih.gov/pubmed/32466293
http://dx.doi.org/10.3390/ijms21103726