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Methanol-Essential Growth of Corynebacterium glutamicum: Adaptive Laboratory Evolution Overcomes Limitation due to Methanethiol Assimilation Pathway

Methanol is a sustainable substrate for biotechnology. In addition to natural methylotrophs, metabolic engineering has gained attention for transfer of methylotrophy. Here, we engineered Corynebacterium glutamicum for methanol-dependent growth with a sugar co-substrate. Heterologous expression of ge...

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Detalles Bibliográficos
Autores principales: Hennig, Guido, Haupka, Carsten, Brito, Luciana F., Rückert, Christian, Cahoreau, Edern, Heux, Stéphanie, Wendisch, Volker F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279501/
https://www.ncbi.nlm.nih.gov/pubmed/32443885
http://dx.doi.org/10.3390/ijms21103617