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iPSCs from people with MS can differentiate into oligodendrocytes in a homeostatic but not an inflammatory milieu

Multiple sclerosis (MS) is an inflammatory and demyelinating disease of the central nervous system (CNS) that results in variable severities of neurodegeneration. The understanding of MS has been limited by the inaccessibility of the affected cells and the lengthy timeframe of disease development. H...

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Detalles Bibliográficos
Autores principales: Morales Pantoja, Itzy E., Smith, Matthew D., Rajbhandari, Labchan, Cheng, Linzhao, Gao, Yongxing, Mahairaki, Vasiliki, Venkatesan, Arun, Calabresi, Peter A., Fitzgerald, Kathryn C., Whartenby, Katharine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279569/
https://www.ncbi.nlm.nih.gov/pubmed/32511247
http://dx.doi.org/10.1371/journal.pone.0233980