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Increased blood-brain barrier hyperpermeability coincides with mast cell activation early under cuprizone administration
The cuprizone induced animal model of demyelination is characterized by demyelination in many regions of the brain with high levels of demyelination in the corpus callosum as well as changes in neuronal function by 4–6 weeks of exposure. The model is used as a tool to study demyelination and subsequ...
Autores principales: | Shelestak, John, Singhal, Naveen, Frankle, Lana, Tomor, Riely, Sternbach, Sarah, McDonough, Jennifer, Freeman, Ernest, Clements, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279587/ https://www.ncbi.nlm.nih.gov/pubmed/32511268 http://dx.doi.org/10.1371/journal.pone.0234001 |
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