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Testisin/Prss21 deficiency causes increased vascular permeability and a hemorrhagic phenotype during luteal angiogenesis

Testisin (encoded by PRSS21) is a membrane anchored serine protease, which is tethered to the cell surface via a glycosylphosphatidylinositol (GPI)-anchor. While testisin is found in abundance in spermatozoa, it is also expressed in microvascular endothelial cells where its function is unknown. Here...

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Detalles Bibliográficos
Autores principales: Peroutka, Raymond J., Buzza, Marguerite S., Mukhopadhyay, Subhradip, Johnson, Tierra A., Driesbaugh, Kathryn H., Antalis, Toni M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279603/
https://www.ncbi.nlm.nih.gov/pubmed/32511276
http://dx.doi.org/10.1371/journal.pone.0234407