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High‐fat diet induced obesity and age influence the telomere shelterin complex and telomerase gene expression in mouse adipose tissue

Obesity and aging are linked to inflammation and increased risk of chronic disease. Telomeres are the endcaps of chromosomes that are regulated by telomerase, the enzyme that elongates telomeres, as well as a protein complex known as shelterin. Telomere dysfunction is associated with inflammation, a...

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Detalles Bibliográficos
Autores principales: Bloom, Samuel I., Tuluca, Andrei, Ives, Stephen J., Reynolds, Thomas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280005/
https://www.ncbi.nlm.nih.gov/pubmed/32512652
http://dx.doi.org/10.14814/phy2.14461