Cargando…
High‐fat diet induced obesity and age influence the telomere shelterin complex and telomerase gene expression in mouse adipose tissue
Obesity and aging are linked to inflammation and increased risk of chronic disease. Telomeres are the endcaps of chromosomes that are regulated by telomerase, the enzyme that elongates telomeres, as well as a protein complex known as shelterin. Telomere dysfunction is associated with inflammation, a...
Autores principales: | Bloom, Samuel I., Tuluca, Andrei, Ives, Stephen J., Reynolds, Thomas H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280005/ https://www.ncbi.nlm.nih.gov/pubmed/32512652 http://dx.doi.org/10.14814/phy2.14461 |
Ejemplares similares
-
The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres
por: Frank, Amanda K., et al.
Publicado: (2015) -
Shelterin Complex at Telomeres: Implications in Ageing
por: Mir, Seyed Mostafa, et al.
Publicado: (2020) -
Differences in Disease Severity but Similar Telomere Lengths in Genetic Subgroups of Patients with Telomerase and Shelterin Mutations
por: Vulliamy, Tom J., et al.
Publicado: (2011) -
A proto-telomere is elongated by telomerase in a shelterin-dependent manner in quiescent fission yeast cells
por: Vaurs, Mélina, et al.
Publicado: (2022) -
Shelterin protein keeps telomeres on edge
por: Leslie, Mitch
Publicado: (2013)