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Activation of the MET receptor attenuates doxorubicin‐induced cardiotoxicity in vivo and in vitro
BACKGROUND AND PURPOSE: Doxorubicin anti‐cancer therapy is associated with cardiotoxicity, resulting from DNA damage response (DDR). Hepatocyte growth factor (HGF) protects cardiomyocytes from injury, but its effective use is compromised by low biodistribution. In this study, we have investigated wh...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280013/ https://www.ncbi.nlm.nih.gov/pubmed/32133617 http://dx.doi.org/10.1111/bph.15039 |