Activation of the MET receptor attenuates doxorubicin‐induced cardiotoxicity in vivo and in vitro

BACKGROUND AND PURPOSE: Doxorubicin anti‐cancer therapy is associated with cardiotoxicity, resulting from DNA damage response (DDR). Hepatocyte growth factor (HGF) protects cardiomyocytes from injury, but its effective use is compromised by low biodistribution. In this study, we have investigated wh...

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Detalles Bibliográficos
Autores principales: Gallo, Simona, Spilinga, Martina, Albano, Raffaella, Ferrauto, Giuseppe, Di Gregorio, Enza, Casanova, Elena, Balmativola, Davide, Bonzano, Alessandro, Boccaccio, Carla, Sapino, Anna, Comoglio, Paolo Maria, Crepaldi, Tiziana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280013/
https://www.ncbi.nlm.nih.gov/pubmed/32133617
http://dx.doi.org/10.1111/bph.15039

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