Transition-metal-free formal cross-coupling of aryl methyl sulfoxides and alcohols via nucleophilic activation of C-S bond

Employment of sulfoxides as electrophiles in cross-coupling reactions remains underexplored. Herein we report a transition-metal-free cross-coupling strategy utilizing aryl(heteroaryl) methyl sulfoxides and alcohols to afford alkyl aryl(heteroaryl) ethers. Two drug molecules were successfully prepar...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Guolin, Nieves-Quinones, Yexenia, Zhang, Hui, Liang, Qingjin, Su, Shuaisong, Liu, Qingchao, Kozlowski, Marisa C., Jia, Tiezheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280189/
https://www.ncbi.nlm.nih.gov/pubmed/32513962
http://dx.doi.org/10.1038/s41467-020-16713-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280189/
https://www.ncbi.nlm.nih.gov/pubmed/32513962
http://dx.doi.org/10.1038/s41467-020-16713-8

Ejemplares similares