Increased AT(2)R expression is induced by AT(1)R autoantibody via two axes, Klf-5/IRF-1 and circErbB4/miR-29a-5p, to promote VSMC migration

Vascular remodeling can be caused by angiotensin II type 1 receptor (AT(1)R) autoantibody (AT1-AA), although the related mechanism remains unknown. Angiotensin II type 2 receptor (AT(2)R) plays multiple roles in vascular remodeling through cross-talk with AT(1)R in the cytoplasm. Here, we aimed to e...

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Detalles Bibliográficos
Autores principales: Sun, Yan, Li, Yang, Wang, Meili, Yue, Mingming, Bai, Lina, Bian, Jingwei, Hao, Weiwei, Sun, Jing, Zhang, Suli, Liu, Huirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280191/
https://www.ncbi.nlm.nih.gov/pubmed/32514012
http://dx.doi.org/10.1038/s41419-020-2643-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280191/
https://www.ncbi.nlm.nih.gov/pubmed/32514012
http://dx.doi.org/10.1038/s41419-020-2643-5

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