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Increased AT(2)R expression is induced by AT(1)R autoantibody via two axes, Klf-5/IRF-1 and circErbB4/miR-29a-5p, to promote VSMC migration
Vascular remodeling can be caused by angiotensin II type 1 receptor (AT(1)R) autoantibody (AT1-AA), although the related mechanism remains unknown. Angiotensin II type 2 receptor (AT(2)R) plays multiple roles in vascular remodeling through cross-talk with AT(1)R in the cytoplasm. Here, we aimed to e...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280191/ https://www.ncbi.nlm.nih.gov/pubmed/32514012 http://dx.doi.org/10.1038/s41419-020-2643-5 |