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The monoclonal antibody Ca37, developed against Candida albicans alcohol dehydrogenase, inhibits the yeast in vitro and in vivo

Candida albicans is a commensal yeast able to cause life threatening invasive infections particularly in immunocompromised patients. Despite the availability of antifungal treatments, mortality rates are still unacceptably high and drug resistance is increasing. We, therefore, generated the Ca37 mon...

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Detalles Bibliográficos
Autores principales: Antoran, Aitziber, Aparicio-Fernandez, Leire, Pellon, Aize, Buldain, Idoia, Martin-Souto, Leire, Rementeria, Aitor, Ghannoum, Mahmoud A., Fuchs, Beth Burgwyn, Mylonakis, Eleftherios, Hernando, Fernando L., Ramirez-Garcia, Andoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280234/
https://www.ncbi.nlm.nih.gov/pubmed/32514067
http://dx.doi.org/10.1038/s41598-020-65859-4