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The monoclonal antibody Ca37, developed against Candida albicans alcohol dehydrogenase, inhibits the yeast in vitro and in vivo
Candida albicans is a commensal yeast able to cause life threatening invasive infections particularly in immunocompromised patients. Despite the availability of antifungal treatments, mortality rates are still unacceptably high and drug resistance is increasing. We, therefore, generated the Ca37 mon...
Autores principales: | Antoran, Aitziber, Aparicio-Fernandez, Leire, Pellon, Aize, Buldain, Idoia, Martin-Souto, Leire, Rementeria, Aitor, Ghannoum, Mahmoud A., Fuchs, Beth Burgwyn, Mylonakis, Eleftherios, Hernando, Fernando L., Ramirez-Garcia, Andoni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280234/ https://www.ncbi.nlm.nih.gov/pubmed/32514067 http://dx.doi.org/10.1038/s41598-020-65859-4 |
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