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Computational modeling to determine key regulators of hypoxia effects on the lactate production in the glycolysis pathway
In solid tumors, hypoxia can trigger aberrant expression of transcription factors and genes, resulting in abnormal biological functions such as altered energetic pathways in cancer cells. Glucose metabolism is an important part of this phenomenon, which is associated with changes in the functional e...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280308/ https://www.ncbi.nlm.nih.gov/pubmed/32514127 http://dx.doi.org/10.1038/s41598-020-66059-w |