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Histone deacetylase inhibitor CG200745 ameliorates high-fat diet-induced hypertension via inhibition of angiotensin II production

Obesity is growing rapidly worldwide due to consumption of westernized diet and lack of exercise. Obesity is one of the major risk factors of hypertension. The novel histone deacetylase (HDAC) inhibitor CG200745 was originally developed to treat various cancers. Previous studies showed that CG200745...

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Detalles Bibliográficos
Autores principales: Yoon, Ga-Eun, Jung, Jin Ki, Lee, Yun-Han, Jang, Byeong-Churl, In Kim, Jee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280340/
https://www.ncbi.nlm.nih.gov/pubmed/31655853
http://dx.doi.org/10.1007/s00210-019-01749-5