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Polygenic analysis of the effect of common and low-frequency genetic variants on serum uric acid levels in Korean individuals

Increased serum uric acid (SUA) levels cause gout and are associated with multiple diseases, including chronic kidney disease. Previous genome-wide association studies (GWAS) have identified more than 180 loci that contribute to SUA levels. Here, we investigated genetic determinants of SUA level in...

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Detalles Bibliográficos
Autores principales: Cho, Sung Kweon, Kim, Beomsu, Myung, Woojae, Chang, Yoosoo, Ryu, Seungho, Kim, Han-Na, Kim, Hyung-Lae, Kuo, Po-Hsiu, Winkler, Cheryl A., Won, Hong-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280503/
https://www.ncbi.nlm.nih.gov/pubmed/32514006
http://dx.doi.org/10.1038/s41598-020-66064-z