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Polygenic analysis of the effect of common and low-frequency genetic variants on serum uric acid levels in Korean individuals
Increased serum uric acid (SUA) levels cause gout and are associated with multiple diseases, including chronic kidney disease. Previous genome-wide association studies (GWAS) have identified more than 180 loci that contribute to SUA levels. Here, we investigated genetic determinants of SUA level in...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280503/ https://www.ncbi.nlm.nih.gov/pubmed/32514006 http://dx.doi.org/10.1038/s41598-020-66064-z |