PIK3C3 regulates the expansion of liver CSCs and PIK3C3 inhibition counteracts liver cancer stem cell activity induced by PI3K inhibitor

The existence of cancer stem cells (CSCs) accounts for hepatocellular carcinoma (HCC) treatment resistance, relapse, and metastasis. Although the elimination of cancer stem cells is crucial for cancer treatment, strategies for their elimination are limited. Here, we report that a remarkable increase...

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Detalles Bibliográficos
Autores principales: Liu, Fengchao, Wu, Xiaoling, Qian, Yanzhi, Jiang, Xin, Wang, Yiying, Gao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280510/
https://www.ncbi.nlm.nih.gov/pubmed/32513919
http://dx.doi.org/10.1038/s41419-020-2631-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280510/
https://www.ncbi.nlm.nih.gov/pubmed/32513919
http://dx.doi.org/10.1038/s41419-020-2631-9

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