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Endogenously produced LG3/4/5-peptide protects testes against toxicant-induced injury

Laminin-α2 chain is one of the major constituent proteins of the basement membrane in the mammalian testis. The laminin-type globular (LG) domains of LG3, 4 and 5 (LG3/4/5, an 80 kDa fragment) can be cleaved from laminin-α2 chain at the C-terminus via the action of matrix metalloproteinase 9 (MMP-9)...

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Detalles Bibliográficos
Autores principales: Li, Linxi, Mao, Baiping, Wu, Siwen, Li, Huitao, Lv, Lixiu, Ge, Renshan, Cheng, C. Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280515/
https://www.ncbi.nlm.nih.gov/pubmed/32513914
http://dx.doi.org/10.1038/s41419-020-2608-8