Structure and dynamics of the ASB9 CUL-RING E3 Ligase

The Cullin 5 (CUL5) Ring E3 ligase uses adaptors Elongins B and C (ELOB/C) to bind different SOCS-box-containing substrate receptors, determining the substrate specificity of the ligase. The 18-member ankyrin and SOCS box (ASB) family is the largest substrate receptor family. Here we report cryo-EM...

Descripción completa

Detalles Bibliográficos
Autores principales: Lumpkin, Ryan J., Baker, Richard W., Leschziner, Andres E., Komives, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280518/
https://www.ncbi.nlm.nih.gov/pubmed/32513959
http://dx.doi.org/10.1038/s41467-020-16499-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280518/
https://www.ncbi.nlm.nih.gov/pubmed/32513959
http://dx.doi.org/10.1038/s41467-020-16499-9

Ejemplares similares