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In-depth Mendelian randomization analysis of causal factors for coronary artery disease

Selecting a set of valid genetic variants is critical for Mendelian randomization (MR) to correctly infer risk factors causing a disease. We here developed a method for selecting genetic variants as valid instrumental variables for inferring risk factors causing coronary artery disease (CAD). Using...

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Detalles Bibliográficos
Autores principales: Tan, Yuan-De, Xiao, Peng, Guda, Chittibabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280530/
https://www.ncbi.nlm.nih.gov/pubmed/32514076
http://dx.doi.org/10.1038/s41598-020-66027-4