Microglia influence host defense, disease, and repair following murine coronavirus infection of the central nervous system

The present study examines functional contributions of microglia in host defense, demyelination, and remyelination following infection of susceptible mice with a neurotropic coronavirus. Treatment with PLX5622, an inhibitor of colony stimulating factor 1 receptor (CSF1R) that efficiently depletes mi...

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Detalles Bibliográficos
Autores principales: Mangale, Vrushali, Syage, Amber R., Ekiz, H. Atakan, Skinner, Dominic D., Cheng, Yuting, Stone, Colleen L., Brown, R. Marshall, O'Connell, Ryan M., Green, Kim N., Lane, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280614/
https://www.ncbi.nlm.nih.gov/pubmed/32449994
http://dx.doi.org/10.1002/glia.23844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280614/
https://www.ncbi.nlm.nih.gov/pubmed/32449994
http://dx.doi.org/10.1002/glia.23844

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