Cargando…

Microglia influence host defense, disease, and repair following murine coronavirus infection of the central nervous system

The present study examines functional contributions of microglia in host defense, demyelination, and remyelination following infection of susceptible mice with a neurotropic coronavirus. Treatment with PLX5622, an inhibitor of colony stimulating factor 1 receptor (CSF1R) that efficiently depletes mi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mangale, Vrushali, Syage, Amber R., Ekiz, H. Atakan, Skinner, Dominic D., Cheng, Yuting, Stone, Colleen L., Brown, R. Marshall, O'Connell, Ryan M., Green, Kim N., Lane, Thomas E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280614/ https://www.ncbi.nlm.nih.gov/pubmed/32449994 http://dx.doi.org/10.1002/glia.23844

Ejemplares similares

Single-Cell RNA Sequencing Reveals the Diversity of the Immunological Landscape following Central Nervous System Infection by a Murine Coronavirus
por: Syage, Amber R., et al.
Publicado: (2020)

Sustained Infiltration of Neutrophils Into the CNS Results in Increased Demyelination in a Viral-Induced Model of Multiple Sclerosis
por: Skinner, Dominic D., et al.
Publicado: (2022)

Induced CNS expression of CXCL1 augments neurologic disease in a murine model of multiple sclerosis via enhanced neutrophil recruitment
por: Grist, Jonathan J., et al.
Publicado: (2018)

CIPR: a web-based R/shiny app and R package to annotate cell clusters in single cell RNA sequencing experiments
por: Ekiz, H. Atakan, et al.
Publicado: (2020)

miR-aculous new avenues for cancer immunotherapy
por: Tang, William W., et al.
Publicado: (2022)

Neural precursor cells derived from induced pluripotent stem cells exhibit reduced susceptibility to infection with a neurotropic coronavirus
por: Mangale, Vrushali, et al.
Publicado: (2017)

Elimination of microglia improves cognitive function following cranial irradiation
por: Acharya, Munjal M., et al.
Publicado: (2016)

Maternal schistosomiasis impairs offspring Interleukin-4 production and B cell expansion
por: Cortés-Selva, Diana, et al.
Publicado: (2021)

Mitigation of helium irradiation-induced brain injury by microglia depletion
por: Allen, Barrett D., et al.
Publicado: (2020)

Defensive pharmacy practice: a gap in our understanding
por: O’Connell, Juliette
Publicado: (2021)

Disrupted macrophage metabolic reprogramming in aged soleus muscle during early recovery following disuse atrophy
por: Fix, Dennis K., et al.
Publicado: (2021)

Interferon Gamma-Inducible NAMPT in Melanoma Cells Serves as a Mechanism of Resistance to Enhance Tumor Growth
por: Barba, Cindy, et al.
Publicado: (2023)

Role of Microglia in Age-Related Changes to the Nervous System
por: Brown, David R.
Publicado: (2009)

Suggestions on Chorea and Allied Nervous Disorders
por: O'Connell, Matthew D.
Publicado: (1881)

Chemokine expression and viral infection of the central nervous system: Regulation of host defense and neuropathology
por: Liu, Michael T., et al.
Publicado: (2001)

The microbiota protects from viral-induced neurologic damage through microglia-intrinsic TLR signaling
por: Brown, D Garrett, et al.
Publicado: (2019)

Phagocytosis of Microglia in the Central Nervous System Diseases
por: Fu, Ruying, et al.
Publicado: (2014)

RON promotes the metastatic spread of breast carcinomas by subverting antitumor immune responses
por: Eyob, Henok, et al.
Publicado: (2013)

Protocol for induction and characterization of microglia extracellular traps in murine and human microglia cells
por: Agrawal, Ishan, et al.
Publicado: (2021)

ELR(+) chemokine signaling in host defense and disease in a viral model of central nervous system disease
por: Hosking, Martin P., et al.
Publicado: (2014)

The importance of microglia in the development of the vasculature in the central nervous system
por: Arnold, Tom, et al.
Publicado: (2013)

Microglia and Macrophages in the Pathological Central and Peripheral Nervous Systems
por: Abe, Naoki, et al.
Publicado: (2020)

Microglia and macrophages of the central nervous system: the contribution of microglia priming and systemic inflammation to chronic neurodegeneration
por: Perry, V. Hugh, et al.
Publicado: (2013)

Innate Immune Responses and Viral-Induced Neurologic Disease
por: Cheng, Yuting, et al.
Publicado: (2018)

Localized microglia dysregulation impairs central nervous system myelination in development
por: Holloway, Rebecca K., et al.
Publicado: (2023)

Pathogenesis of Murine Coronavirus in the Central Nervous System
por: Bender, Susan J., et al.
Publicado: (2010)

TREM2 is down-regulated by HSV1 in microglia and involved in antiviral defense in the brain
por: Fruhwürth, Stefanie, et al.
Publicado: (2023)

Microglia do not restrict SARS-CoV-2 replication following infection of the central nervous system of K18-hACE2 transgenic mice
por: Olivarria, Gema M., et al.
Publicado: (2021)

Microglia Do Not Restrict SARS-CoV-2 Replication following Infection of the Central Nervous System of K18-Human ACE2 Transgenic Mice
por: Olivarria, Gema M., et al.
Publicado: (2022)

Interleukin 1 of the central nervous system is produced by ameboid microglia
Publicado: (1986)

Differential roles of microglia and monocytes in the inflamed central nervous system
por: Yamasaki, Ryo, et al.
Publicado: (2014)

Correction: The importance of microglia in the development of the vasculature in the central nervous system
por: Arnold, Tom, et al.
Publicado: (2013)

The Gut-Microglia Connection: Implications for Central Nervous System Diseases
por: Wang, Yiliang, et al.
Publicado: (2018)

Central nervous system regeneration is driven by microglia necroptosis and repopulation
por: Lloyd, Amy F., et al.
Publicado: (2019)

MicroRNAs of microglia: wrestling with central nervous system disease
por: Wang, Xiao-Hua, et al.
Publicado: (2018)

Microglia/macrophage diversities in central nervous system physiology and pathology
por: Xie, Di, et al.
Publicado: (2019)

Microglia regulate central nervous system myelin growth and integrity
por: McNamara, Niamh B., et al.
Publicado: (2022)

Microglia regulate the health of central nervous system through myelin
por: Niu, Xin, et al.
Publicado: (2023)

Antioxidant Defense Mechanisms in Erythrocytes and in the Central Nervous System
por: Franco, Rafael, et al.
Publicado: (2019)

Culture and Characterization of Microglia from the Adult Murine Retina
por: Devarajan, Gayathri, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_qjn4dmtobnjp8h939605ktlltf