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The Se(…)S/N interactions as a possible mechanism of δ-aminolevulinic acid dehydratase enzyme inhibition by organoselenium compounds: A computational study

Organoselenium compounds present many pharmacological properties and are promising drugs. However, toxicological effects associated with inhibition of thiol-containing enzymes, such as the δ-aminolevulinic acid dehydratase (δ-AlaD), have been described. The molecular mechanism(s) by which they inhib...

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Detalles Bibliográficos
Autores principales: Nogara, Pablo Andrei, Orian, Laura, Rocha, João Batista Teixeira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280828/
https://www.ncbi.nlm.nih.gov/pubmed/32572387
http://dx.doi.org/10.1016/j.comtox.2020.100127