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From Basic Immunology to Clinical Practice: Bio-Originators versus Bio-Similars
Biologic agents are macromolecules, and as such, they have a high level of structural heterogeneity. Treatment with such agents has been extremely expensive limiting thus their availability to increasing numbers of patients; therefore, many manufacturers chose to develop biologics that are highly si...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Mediterranean Journal of Rheumatology (MJR)
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280872/ https://www.ncbi.nlm.nih.gov/pubmed/32524078 http://dx.doi.org/10.31138/mjr.30.1.54 |