A Novel Role for NUAK1 in Promoting Ovarian Cancer Metastasis through Regulation of Fibronectin Production in Spheroids

Epithelial ovarian cancer (EOC) has a unique mode of metastasis, where cells shed from the primary tumour, form aggregates called spheroids to evade anoikis, spread through the peritoneal cavity, and adhere to secondary sites. We previously showed that the master kinase Liver kinase B1 (LKB1) is req...

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Detalles Bibliográficos
Autores principales: Fritz, Jamie Lee, Collins, Olga, Saxena, Parima, Buensuceso, Adrian, Ramos Valdes, Yudith, Francis, Kyle E., Brown, Kevin R., Larsen, Brett, Colwill, Karen, Gingras, Anne-Claude, Rottapel, Robert, Shepherd, Trevor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280971/
https://www.ncbi.nlm.nih.gov/pubmed/32429240
http://dx.doi.org/10.3390/cancers12051250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280971/
https://www.ncbi.nlm.nih.gov/pubmed/32429240
http://dx.doi.org/10.3390/cancers12051250

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