The Progressive Mutagenic Effects of Acidic Bile Refluxate in Hypopharyngeal Squamous Cell Carcinogenesis: New Insights

Cancers of the laryngopharynx represent the most devastating of the head and neck malignancies and additional risk factors are now epidemiologically linked to this disease. Using an in vivo model (Mus musculus C57Bl/6J), we provide novel evidence that acidic bile (pH 3.0) progressively promotes inva...

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Detalles Bibliográficos
Autores principales: Sasaki, Clarence T., Doukas, Sotirios G., Costa, Jose, Vageli, Dimitra P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281001/
https://www.ncbi.nlm.nih.gov/pubmed/32344873
http://dx.doi.org/10.3390/cancers12051064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281001/
https://www.ncbi.nlm.nih.gov/pubmed/32344873
http://dx.doi.org/10.3390/cancers12051064

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