Novel Oncolytic Virus Armed with Cancer Suicide Gene and Normal Vasculogenic Gene for Improved Anti-Tumor Activity

Here, we developed a novel oncolytic vaccinia virus (NOV) with the dual advantages of cancer selectivity and normal vessel reconstructive activity by replacing the viral thymidine kinase (vTk) and vaccinia growth factor (VGF) genes with genes encoding TNF-related apoptosis-inducing ligand (TRAIL) an...

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Detalles Bibliográficos
Autores principales: Jeong, Su-Nam, Yoo, So Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281019/
https://www.ncbi.nlm.nih.gov/pubmed/32344903
http://dx.doi.org/10.3390/cancers12051070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281019/
https://www.ncbi.nlm.nih.gov/pubmed/32344903
http://dx.doi.org/10.3390/cancers12051070

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