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Tumorigenic and Metastatic Role of CD44(−/low)/CD24(−/low) Cells in Luminal Breast Cancer

Cells with high CD44 but low CD24 expression (CD44(high)/CD24(−/low)) and high aldehyde dehydrogenase activity (ALDH(br)) are widely considered to be drivers of metastasis, therapy resistance and tumor recurrence in breast cancer. However, the role of the CD44(high)/CD24(−/low) and ALDH(br) phenotyp...

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Detalles Bibliográficos
Autores principales: Vikram, Rajeev, Chou, Wen Cheng, Hung, Shih-Chieh, Shen, Chen-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281029/
https://www.ncbi.nlm.nih.gov/pubmed/32423137
http://dx.doi.org/10.3390/cancers12051239