Deactivation of Glutaminolysis Sensitizes PIK3CA-Mutated Colorectal Cancer Cells to Aspirin-Induced Growth Inhibition

Aspirin is one of the most promising over-the-counter drugs to repurpose for cancer treatment. In particular, aspirin has been reported to be effective against PIK3CA-mutated colorectal cancer (CRC); however, little information is available on how the PIK3CA gene status affects its efficacy. We foun...

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Detalles Bibliográficos
Autores principales: Boku, Shogen, Watanabe, Motoki, Sukeno, Mamiko, Yaoi, Takeshi, Hirota, Kiichi, Iizuka-Ohashi, Mahiro, Itoh, Kyoko, Sakai, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281071/
https://www.ncbi.nlm.nih.gov/pubmed/32365457
http://dx.doi.org/10.3390/cancers12051097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281071/
https://www.ncbi.nlm.nih.gov/pubmed/32365457
http://dx.doi.org/10.3390/cancers12051097

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