WRN-Mutated Colorectal Cancer Is Characterized by a Distinct Genetic Phenotype

Werner syndrome gene (WRN) contributes to DNA repair. In cancer, WRN mutations (WRN-mut) lead to genomic instability. Thus, WRN is a promising target in cancers with microsatellite instability (MSI). We assessed this study to investigate the molecular profile of WRN-mut in colorectal cancer (CRC). T...

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Detalles Bibliográficos
Autores principales: Zimmer, Kai, Puccini, Alberto, Xiu, Joanne, Baca, Yasmine, Spizzo, Gilbert, Lenz, Heinz-Josef, Battaglin, Francesca, Goldberg, Richard M., Grothey, Axel, Shields, Anthony F., Salem, Mohamed E., Marshall, John L., Korn, W. Michael, Wolf, Dominik, Kocher, Florian, Seeber, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281075/
https://www.ncbi.nlm.nih.gov/pubmed/32455893
http://dx.doi.org/10.3390/cancers12051319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281075/
https://www.ncbi.nlm.nih.gov/pubmed/32455893
http://dx.doi.org/10.3390/cancers12051319

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