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Co-Expression of Androgen Receptor and Cathepsin D Defines a Triple-Negative Breast Cancer Subgroup with Poorer Overall Survival

Background: In the triple-negative breast cancer (TNBC) group, the luminal androgen receptor subtype is characterized by expression of androgen receptor (AR) and lack of estrogen receptor and cytokeratin 5/6 expression. Cathepsin D (Cath-D) is overproduced and hypersecreted by breast cancer (BC) cel...

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Detalles Bibliográficos
Autores principales: Mansouri, Hanane, Alcaraz, Lindsay B., Mollevi, Caroline, Mallavialle, Aude, Jacot, William, Boissière-Michot, Florence, Simony-Lafontaine, Joelle, Laurent-Matha, Valérie, Roger, Pascal, Liaudet-Coopman, Emmanuelle, Guiu, Séverine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281089/
https://www.ncbi.nlm.nih.gov/pubmed/32429078
http://dx.doi.org/10.3390/cancers12051244