FAK Inhibition Induces Glioblastoma Cell Senescence-Like State through p62 and p27

Focal adhesion kinase (FAK) is a central component of focal adhesions that regulate cancer cell proliferation and migration. Here, we studied the effects of FAK inhibition in glioblastoma (GBM), a fast growing brain tumor that has a poor prognosis. Treating GBM cells with the FAK inhibitor PF-573228...

Descripción completa

Detalles Bibliográficos
Autores principales: Alza, Lía, Nàger, Mireia, Visa, Anna, Cantí, Carles, Herreros, Judit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281094/
https://www.ncbi.nlm.nih.gov/pubmed/32349327
http://dx.doi.org/10.3390/cancers12051086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281094/
https://www.ncbi.nlm.nih.gov/pubmed/32349327
http://dx.doi.org/10.3390/cancers12051086

Ejemplares similares