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FAK Inhibition Induces Glioblastoma Cell Senescence-Like State through p62 and p27

Focal adhesion kinase (FAK) is a central component of focal adhesions that regulate cancer cell proliferation and migration. Here, we studied the effects of FAK inhibition in glioblastoma (GBM), a fast growing brain tumor that has a poor prognosis. Treating GBM cells with the FAK inhibitor PF-573228...

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Detalles Bibliográficos
Autores principales:	Alza, Lía, Nàger, Mireia, Visa, Anna, Cantí, Carles, Herreros, Judit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281094/ https://www.ncbi.nlm.nih.gov/pubmed/32349327 http://dx.doi.org/10.3390/cancers12051086

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