Nelfinavir Inhibits the TCF11/Nrf1-Mediated Proteasome Recovery Pathway in Multiple Myeloma

Proteasome inhibitors are the backbone of multiple myeloma therapy. However, disease progression or early relapse occur due to development of resistance to the therapy. One important cause of resistance to proteasome inhibition is the so-called bounce-back response, a recovery pathway driven by the...

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Detalles Bibliográficos
Autores principales: Fassmannová, Dominika, Sedlák, František, Sedláček, Jindřich, Špička, Ivan, Grantz Šašková, Klára
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281108/
https://www.ncbi.nlm.nih.gov/pubmed/32344880
http://dx.doi.org/10.3390/cancers12051065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281108/
https://www.ncbi.nlm.nih.gov/pubmed/32344880
http://dx.doi.org/10.3390/cancers12051065

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