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Nelfinavir Inhibits the TCF11/Nrf1-Mediated Proteasome Recovery Pathway in Multiple Myeloma
Proteasome inhibitors are the backbone of multiple myeloma therapy. However, disease progression or early relapse occur due to development of resistance to the therapy. One important cause of resistance to proteasome inhibition is the so-called bounce-back response, a recovery pathway driven by the...
Autores principales: | Fassmannová, Dominika, Sedlák, František, Sedláček, Jindřich, Špička, Ivan, Grantz Šašková, Klára |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281108/ https://www.ncbi.nlm.nih.gov/pubmed/32344880 http://dx.doi.org/10.3390/cancers12051065 |
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