Hakin-1, a New Specific Small-Molecule Inhibitor for the E3 Ubiquitin-Ligase Hakai, Inhibits Carcinoma Growth and Progression

The requirement of the E3 ubiquitin-ligase Hakai for the ubiquitination and subsequent degradation of E-cadherin has been associated with enhanced epithelial-to-mesenchymal transition (EMT), tumour progression and carcinoma metastasis. To date, most of the reported EMT-related inhibitors were not de...

Descripción completa

Detalles Bibliográficos
Autores principales: Martinez-Iglesias, Olaia, Casas-Pais, Alba, Castosa, Raquel, Díaz-Díaz, Andrea, Roca-Lema, Daniel, Concha, Ángel, Cortés, Álvaro, Gago, Federico, Figueroa, Angélica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281109/
https://www.ncbi.nlm.nih.gov/pubmed/32456234
http://dx.doi.org/10.3390/cancers12051340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281109/
https://www.ncbi.nlm.nih.gov/pubmed/32456234
http://dx.doi.org/10.3390/cancers12051340

Ejemplares similares