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Hakin-1, a New Specific Small-Molecule Inhibitor for the E3 Ubiquitin-Ligase Hakai, Inhibits Carcinoma Growth and Progression

The requirement of the E3 ubiquitin-ligase Hakai for the ubiquitination and subsequent degradation of E-cadherin has been associated with enhanced epithelial-to-mesenchymal transition (EMT), tumour progression and carcinoma metastasis. To date, most of the reported EMT-related inhibitors were not de...

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Detalles Bibliográficos
Autores principales:	Martinez-Iglesias, Olaia, Casas-Pais, Alba, Castosa, Raquel, Díaz-Díaz, Andrea, Roca-Lema, Daniel, Concha, Ángel, Cortés, Álvaro, Gago, Federico, Figueroa, Angélica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281109/ https://www.ncbi.nlm.nih.gov/pubmed/32456234 http://dx.doi.org/10.3390/cancers12051340

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