Multimodal Targeted Deep Sequencing of Circulating Tumor Cells and Matched Cell-Free DNA Provides a More Comprehensive Tool to Identify Therapeutic Targets in Metastatic Breast Cancer Patients

Cell-free DNA (cfDNA) and circulating tumor cells (CTCs) exhibit great potential for therapy management in oncology. We aimed to establish a multimodal liquid biopsy strategy that is usable with minimized blood volume to deconvolute the genomic complexity of metastatic breast cancer. CTCs were isola...

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Detalles Bibliográficos
Autores principales: Keup, Corinna, Storbeck, Markus, Hauch, Siegfried, Hahn, Peter, Sprenger-Haussels, Markus, Hoffmann, Oliver, Kimmig, Rainer, Kasimir-Bauer, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281124/
https://www.ncbi.nlm.nih.gov/pubmed/32349306
http://dx.doi.org/10.3390/cancers12051084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281124/
https://www.ncbi.nlm.nih.gov/pubmed/32349306
http://dx.doi.org/10.3390/cancers12051084

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