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Multimodal Targeted Deep Sequencing of Circulating Tumor Cells and Matched Cell-Free DNA Provides a More Comprehensive Tool to Identify Therapeutic Targets in Metastatic Breast Cancer Patients
Cell-free DNA (cfDNA) and circulating tumor cells (CTCs) exhibit great potential for therapy management in oncology. We aimed to establish a multimodal liquid biopsy strategy that is usable with minimized blood volume to deconvolute the genomic complexity of metastatic breast cancer. CTCs were isola...
Autores principales: | Keup, Corinna, Storbeck, Markus, Hauch, Siegfried, Hahn, Peter, Sprenger-Haussels, Markus, Hoffmann, Oliver, Kimmig, Rainer, Kasimir-Bauer, Sabine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281124/ https://www.ncbi.nlm.nih.gov/pubmed/32349306 http://dx.doi.org/10.3390/cancers12051084 |
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