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Identification of Distinct Heterogenic Subtypes and Molecular Signatures Associated with African Ancestry in Triple Negative Breast Cancer Using Quantified Genetic Ancestry Models in Admixed Race Populations

Triple negative breast cancers (TNBCs) are molecularly heterogeneous, and the link between their aggressiveness with African ancestry is not established. We investigated primary TNBCs for gene expression among self-reported race (SRR) groups of African American (AA, n = 42) and European American (EA...

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Detalles Bibliográficos
Autores principales: Davis, Melissa, Martini, Rachel, Newman, Lisa, Elemento, Olivier, White, Jason, Verma, Akanksha, Datta, Indrani, Adrianto, Indra, Chen, Yalei, Gardner, Kevin, Kim, Hyung-Gyoon, Colomb, Windy D., Eltoum, Isam-Eldin, Frost, Andra R., Grizzle, William E., Sboner, Andrea, Manne, Upender, Yates, Clayton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281131/
https://www.ncbi.nlm.nih.gov/pubmed/32414099
http://dx.doi.org/10.3390/cancers12051220