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Targeting EpCAM by a Bispecific Trifunctional Antibody Exerts Profound Cytotoxic Efficacy in Germ Cell Tumor Cell Lines

Outcome in high-risk patients with refractory or relapsed germ cell tumours (GCT) remains poor. Novel strategies enhancing therapeutic efficacy whilst limiting therapeutic burden are warranted, yet immunotherapy approaches geared towards activating endogenous antitumor responses have not been succes...

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Detalles Bibliográficos
Autores principales: Schönberger, Stefan, Kraft, Daniela, Nettersheim, Daniel, Schorle, Hubert, Casati, Anna, Craveiro, Rogerio B., Mohseni, Mahsa Mir, Calaminus, Gabriele, Dilloo, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281168/
https://www.ncbi.nlm.nih.gov/pubmed/32438548
http://dx.doi.org/10.3390/cancers12051279