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The Proteasome Inhibitor Ixazomib Inhibits the Formation and Growth of Pulmonary and Abdominal Osteosarcoma Metastases in Mice

Osteosarcoma is the most common form of primary bone cancer. Over 20% of osteosarcoma patients present with pulmonary metastases at diagnosis, and nearly 70% of these patients fail to respond to treatment. Previous work revealed that human and canine osteosarcoma cell lines are extremely sensitive t...

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Detalles Bibliográficos
Autores principales: Harris, Michael A., Miles, Mark A., Shekhar, Tanmay M., Cerra, Carmelo, Georgy, Smitha R., Ryan, Stewart D., Cannon, Claire M., Hawkins, Christine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281181/
https://www.ncbi.nlm.nih.gov/pubmed/32403415
http://dx.doi.org/10.3390/cancers12051207