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Thioholgamide A, a New Anti-Proliferative Anti-Tumor Agent, Modulates Macrophage Polarization and Metabolism

Natural products represent powerful tools searching for novel anticancer drugs. Thioholgamide A (thioA) is a ribosomally synthesized and post-translationally modified peptide, which has been identified as a product of Streptomyces sp. MUSC 136T. In this study, we provide a comprehensive biological p...

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Detalles Bibliográficos
Autores principales: Dahlem, Charlotte, Siow, Wei Xiong, Lopatniuk, Maria, Tse, William K. F., Kessler, Sonja M., Kirsch, Susanne H., Hoppstädter, Jessica, Vollmar, Angelika M., Müller, Rolf, Luzhetskyy, Andriy, Bartel, Karin, Kiemer, Alexandra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281193/
https://www.ncbi.nlm.nih.gov/pubmed/32438733
http://dx.doi.org/10.3390/cancers12051288